Prophecy centers entirely around the origins of the Bene Gesserit, known only as "the Sisterhood" in the show. However, there's a very simple reason for that. "The Sisterhood at its inception is not called the Bene Gesserit,

Since its 2021 release, Dune has captivated audiences with its epic tales set on the spice-rich planet Arrakis. The movie—based on Frank Herbert’s best-selling Dune books—follows Paul Atreides (Timothée Chalamet) as he travels to the planet Arrakis in the hopes of bringing their beloved “spice” to his family's allies.

Prophecy, the Bene Gesserit organization is under the leadership of Mother Superior Valya Harkonnen (Emily Watson), its second leader, following the passing of Raquella Berto-Anirul. Valya is a conflicted individual - she is loyal to the Sisterhood but still feels some tie to her exiled and disgraced family.